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Ngn1 inhibits astrogliogenesis through induction of miR-9 during neuronal fate specification

It has been postulated that a proneural factor, neurogenin 1 (Ngn1), simultaneously activates the neurogenic program and inhibits the alternative astrogliogenic program when specifying the neuronal fate. While Ngn1 substantially suppresses the activation of the astrogliogenic Jak-Stat pathway, the u...

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Detalles Bibliográficos
Autores principales: Zhao, Jing, Lin, Quan, Kim, Kevin J, Dardashti, Faranak D, Kim, Jennifer, He, Fei, Sun, Yi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4577824/
https://www.ncbi.nlm.nih.gov/pubmed/26271009
http://dx.doi.org/10.7554/eLife.06885