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Multicongenic fate mapping quantification of dynamics of thymus colonization

Postnatal T cell development depends on continuous colonization of the thymus by BM-derived T lineage progenitors. Both quantitative parameters and the mechanisms of thymus seeding remain poorly understood. Here, we determined the number of dedicated thymus-seeding progenitor niches (TSPNs) capable...

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Detalles Bibliográficos
Autores principales: Ziętara, Natalia, Łyszkiewicz, Marcin, Puchałka, Jacek, Witzlau, Katrin, Reinhardt, Annika, Förster, Reinhold, Pabst, Oliver, Prinz, Immo, Krueger, Andreas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4577840/
https://www.ncbi.nlm.nih.gov/pubmed/26347471
http://dx.doi.org/10.1084/jem.20142143