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An Effective Strategy for Stabilizing Minimal Coiled Coil Mimetics

[Image: see text] Coiled coils are a major motif in proteins and orchestrate multimerization of various complexes important for biological processes. Inhibition of coiled coil-mediated interactions has significant biomedical potential. However, general approaches that afford short peptides with defi...

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Detalles Bibliográficos
Autores principales: Wuo, Michael G., Mahon, Andrew B., Arora, Paramjit S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2015
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4577959/
https://www.ncbi.nlm.nih.gov/pubmed/26340721
http://dx.doi.org/10.1021/jacs.5b05525