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An Effective Strategy for Stabilizing Minimal Coiled Coil Mimetics
[Image: see text] Coiled coils are a major motif in proteins and orchestrate multimerization of various complexes important for biological processes. Inhibition of coiled coil-mediated interactions has significant biomedical potential. However, general approaches that afford short peptides with defi...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Chemical
Society
2015
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4577959/ https://www.ncbi.nlm.nih.gov/pubmed/26340721 http://dx.doi.org/10.1021/jacs.5b05525 |