DNA methylation patterns in naïve CD4+ T cells identify epigenetic susceptibility loci for malar rash and discoid rash in systemic lupus erythematosus

OBJECTIVE: Systemic lupus erythematosus (SLE) is a complex autoimmune disease characterised by heterogeneous clinical manifestations, autoantibody production and epigenetic dysregulation in T cells. We sought to investigate the epigenetic contribution to the development of cutaneous manifestations i...

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Detalles Bibliográficos
Autores principales: Renauer, Paul, Coit, Patrick, Jeffries, Matlock A, Merrill, Joan T, McCune, W Joseph, Maksimowicz-McKinnon, Kathleen, Sawalha, Amr H
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2015
Materias:
Genetics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4577980/
https://www.ncbi.nlm.nih.gov/pubmed/26405558
http://dx.doi.org/10.1136/lupus-2015-000101

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4577980/
https://www.ncbi.nlm.nih.gov/pubmed/26405558
http://dx.doi.org/10.1136/lupus-2015-000101

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