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Analysis of the intra- and intertumoral heterogeneity of hypoxia in pancreatic cancer patients receiving the nitroimidazole tracer pimonidazole

BACKGROUND: Hypoxia is thought to be an adverse feature of pancreatic cancer, but direct measurement in patients is technically challenging. To address this, we characterised the intra/interpatient heterogeneity of hypoxia in surgical specimens from patients who received the 2-nitroimidazole tracer...

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Detalles Bibliográficos
Autores principales: Dhani, N C, Serra, S, Pintilie, M, Schwock, J, Xu, J, Gallinger, S, Hill, R P, Hedley, D W
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4578083/
https://www.ncbi.nlm.nih.gov/pubmed/26325106
http://dx.doi.org/10.1038/bjc.2015.284