A structural model of the anaphase promoting complex co-activator (Cdh1) and in silico design of inhibitory compounds

Anaphase promoting complex (APC) controls cell cycle and chromosome segregation. The APC activation occurs after binding of co-activators, cdh1 and cdc20. Cdh1 plays a role in cancer pathogenesis and is known as a potential drug target. The main aim of this study was prediction of 3D structure of cd...

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Detalles Bibliográficos
Autores principales: Rahimi, H., Negahdari, B., Shokrgozar, M.A., Madadkar-Sobhani, A., Mahdian, R., Foroumadi, A., Amin, M. Kafshdouzi, Karimipoor, M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Medknow Publications & Media Pvt Ltd 2015
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4578213/
https://www.ncbi.nlm.nih.gov/pubmed/26430458

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4578213/
https://www.ncbi.nlm.nih.gov/pubmed/26430458

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