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Integrating genetics and epigenetics in breast cancer: biological insights, experimental, computational methods and therapeutic potential
BACKGROUND: Development of human cancer can proceed through the accumulation of different genetic changes affecting the structure and function of the genome. Combined analyses of molecular data at multiple levels, such as DNA copy-number alteration, mRNA and miRNA expression, can clarify biological...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4578257/ https://www.ncbi.nlm.nih.gov/pubmed/26391647 http://dx.doi.org/10.1186/s12918-015-0211-x |