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Integrating genetics and epigenetics in breast cancer: biological insights, experimental, computational methods and therapeutic potential

BACKGROUND: Development of human cancer can proceed through the accumulation of different genetic changes affecting the structure and function of the genome. Combined analyses of molecular data at multiple levels, such as DNA copy-number alteration, mRNA and miRNA expression, can clarify biological...

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Detalles Bibliográficos
Autores principales: Cava, Claudia, Bertoli, Gloria, Castiglioni, Isabella
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4578257/
https://www.ncbi.nlm.nih.gov/pubmed/26391647
http://dx.doi.org/10.1186/s12918-015-0211-x