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4′-O-β-d-glucosyl-5-O-methylvisamminol, an active ingredient of Saposhnikovia divaricata, attenuates high-mobility group box 1 and subarachnoid hemorrhage-induced vasospasm in a rat model

BACKGROUND: High-mobility group box 1 (HMGB1) was observed to be an important extracellular mediator involved in vascular inflammation associated with subarachnoid hemorrhage (SAH). This study is of interest to examine the efficacy of 4′-O-β-d-glucosyl-5-O-methylvisamminol (4OGOMV), C(22)H(28)O(10),...

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Detalles Bibliográficos
Autores principales: Chang, Chih-Zen, Wu, Shu-Chuan, Kwan, Aij-Lie, Lin, Chih-Lung
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4578329/
https://www.ncbi.nlm.nih.gov/pubmed/26395442
http://dx.doi.org/10.1186/s12993-015-0074-8