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Cooperative and alternate functions for STIM1 and STIM2 in macrophage activation and in the context of inflammation

Calcium (Ca(2+)) signaling in immune cells, including macrophages, controls a wide range of effector functions that are critical for host defense and contribute to inflammation and autoimmune diseases. However, receptor-mediated Ca(2+) responses consist of complex mechanisms that make it difficult t...

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Detalles Bibliográficos
Autores principales: Sogkas, Georgios, Stegner, David, Syed, Shahzad N, Vögtle, Timo, Rau, Eduard, Gewecke, Britta, Schmidt, Reinhold E, Nieswandt, Bernhard, Gessner, Johannes Engelbert
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons, Ltd 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4578517/
https://www.ncbi.nlm.nih.gov/pubmed/26417434
http://dx.doi.org/10.1002/iid3.56