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Neonatal microbial colonization in mice promotes prolonged dominance of CD11b(+)Gr-1(+) cells and accelerated establishment of the CD4(+) T cell population in the spleen

To assess the microbial influence on postnatal hematopoiesis, we examined the role of early life microbial colonization on the composition of leukocyte subsets in the neonatal spleen. A high number of CD11b(+)Gr-1(+) splenocytes present perinatally was sustained for a longer period in conventionally...

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Detalles Bibliográficos
Autores principales: Kristensen, Matilde B, Metzdorff, Stine B, Bergström, Anders, Damlund, Dina S M, Fink, Lisbeth N, Licht, Tine R, Frøkiær, Hanne
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons, Ltd 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4578529/
https://www.ncbi.nlm.nih.gov/pubmed/26417445
http://dx.doi.org/10.1002/iid3.70