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Hyperoxia promotes polarization of the immune response in ovalbumin-induced airway inflammation, leading to a TH(17) cell phenotype

Previous studies have demonstrated that hyperoxia-induced stress and oxidative damage to the lungs of mice lead to an increase in IL-6, TNF-α, and TGF-β expression. Together, IL-6 and TGF-β have been known to direct T cell differentiation toward the TH(17) phenotype. In the current study, we tested...

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Detalles Bibliográficos
Autores principales: Nagato, Akinori C, Bezerra, Frank S, Talvani, André, Aarestrup, Beatriz J, Aarestrup, Fernando M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons, Ltd 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4578530/
https://www.ncbi.nlm.nih.gov/pubmed/26417446
http://dx.doi.org/10.1002/iid3.71