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Hyperoxia promotes polarization of the immune response in ovalbumin-induced airway inflammation, leading to a TH(17) cell phenotype
Previous studies have demonstrated that hyperoxia-induced stress and oxidative damage to the lungs of mice lead to an increase in IL-6, TNF-α, and TGF-β expression. Together, IL-6 and TGF-β have been known to direct T cell differentiation toward the TH(17) phenotype. In the current study, we tested...
Autores principales: | Nagato, Akinori C, Bezerra, Frank S, Talvani, André, Aarestrup, Beatriz J, Aarestrup, Fernando M |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley & Sons, Ltd
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4578530/ https://www.ncbi.nlm.nih.gov/pubmed/26417446 http://dx.doi.org/10.1002/iid3.71 |
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