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The ADAM15 ectodomain is shed from secretory exosomes

We demonstrated previously that a disintegrin and metalloproteinase 15 (ADAM15) is released into the extracellular space as an exosomal component, and that ADAM15-rich exosomes have tumor suppressive functions. However, the suppressive mechanism of ADAM15-rich exosomes remains unclear. In this study...

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Detalles Bibliográficos
Autores principales: Lee, Hee Doo, Kim, Yeon Hyang, Koo, Bon-Hun, Kim, Doo-Sik
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Korean Society for Biochemistry and Molecular Biology 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4578567/
https://www.ncbi.nlm.nih.gov/pubmed/25208722
http://dx.doi.org/10.5483/BMBRep.2015.48.5.161