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NDRG3-mediated lactate signaling in hypoxia

Hypoxia is associated with many pathological conditions as well as the normal physiology of metazoans. We identified a lactate-dependent signaling pathway in hypoxia, mediated by the oxygen- and lactate-regulated protein NDRG family member 3 (NDRG3). Oxygen negatively regulates NDRG3 expression at t...

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Detalles Bibliográficos
Autores principales: Park, Kyung Chan, Lee, Dong Chul, Yeom, Young Il
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Korean Society for Biochemistry and Molecular Biology 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4578614/
https://www.ncbi.nlm.nih.gov/pubmed/25936780
http://dx.doi.org/10.5483/BMBRep.2015.48.6.080