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Statistical significance approximation in local trend analysis of high-throughput time-series data using the theory of Markov chains
BACKGROUND: Local trend (i.e. shape) analysis of time series data reveals co-changing patterns in dynamics of biological systems. However, slow permutation procedures to evaluate the statistical significance of local trend scores have limited its applications to high-throughput time series data anal...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4578688/ https://www.ncbi.nlm.nih.gov/pubmed/26390921 http://dx.doi.org/10.1186/s12859-015-0732-8 |