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ATGme: Open-source web application for rare codon identification and custom DNA sequence optimization

BACKGROUND: Codon usage plays a crucial role when recombinant proteins are expressed in different organisms. This is especially the case if the codon usage frequency of the organism of origin and the target host organism differ significantly, for example when a human gene is expressed in E. coli. Th...

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Detalles Bibliográficos
Autores principales: Daniel, Edward, Onwukwe, Goodluck U., Wierenga, Rik K., Quaggin, Susan E., Vainio, Seppo J., Krause, Mirja
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4578782/
https://www.ncbi.nlm.nih.gov/pubmed/26391121
http://dx.doi.org/10.1186/s12859-015-0743-5