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ATGme: Open-source web application for rare codon identification and custom DNA sequence optimization
BACKGROUND: Codon usage plays a crucial role when recombinant proteins are expressed in different organisms. This is especially the case if the codon usage frequency of the organism of origin and the target host organism differ significantly, for example when a human gene is expressed in E. coli. Th...
Autores principales: | Daniel, Edward, Onwukwe, Goodluck U., Wierenga, Rik K., Quaggin, Susan E., Vainio, Seppo J., Krause, Mirja |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4578782/ https://www.ncbi.nlm.nih.gov/pubmed/26391121 http://dx.doi.org/10.1186/s12859-015-0743-5 |
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