Cargando…

Role of Cbl-PI3K Interaction during Skeletal Remodeling in a Murine Model of Bone Repair

Mice in which Cbl is unable to bind PI3K (YF mice) display increased bone volume due to enhanced bone formation and repressed bone resorption during normal bone homeostasis. We investigated the effects of disrupted Cbl-PI3K interaction on fracture healing to determine whether this interaction has an...

Descripción completa

Detalles Bibliográficos
Autores principales: Scanlon, Vanessa, Soung, Do Yu, Adapala, Naga Suresh, Morgan, Elise, Hansen, Marc F., Drissi, Hicham, Sanjay, Archana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4578922/
https://www.ncbi.nlm.nih.gov/pubmed/26393915
http://dx.doi.org/10.1371/journal.pone.0138194