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Role of Cbl-PI3K Interaction during Skeletal Remodeling in a Murine Model of Bone Repair
Mice in which Cbl is unable to bind PI3K (YF mice) display increased bone volume due to enhanced bone formation and repressed bone resorption during normal bone homeostasis. We investigated the effects of disrupted Cbl-PI3K interaction on fracture healing to determine whether this interaction has an...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4578922/ https://www.ncbi.nlm.nih.gov/pubmed/26393915 http://dx.doi.org/10.1371/journal.pone.0138194 |