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Co-Inheritance Analysis within the Domains of Life Substantially Improves Network Inference by Phylogenetic Profiling
Phylogenetic profiling, a network inference method based on gene inheritance profiles, has been widely used to construct functional gene networks in microbes. However, its utility for network inference in higher eukaryotes has been limited. An improved algorithm with an in-depth understanding of pat...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4578931/ https://www.ncbi.nlm.nih.gov/pubmed/26394049 http://dx.doi.org/10.1371/journal.pone.0139006 |