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Co-Inheritance Analysis within the Domains of Life Substantially Improves Network Inference by Phylogenetic Profiling

Phylogenetic profiling, a network inference method based on gene inheritance profiles, has been widely used to construct functional gene networks in microbes. However, its utility for network inference in higher eukaryotes has been limited. An improved algorithm with an in-depth understanding of pat...

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Detalles Bibliográficos
Autores principales: Shin, Junha, Lee, Insuk
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4578931/
https://www.ncbi.nlm.nih.gov/pubmed/26394049
http://dx.doi.org/10.1371/journal.pone.0139006