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Decoding Structural Properties of a Partially Unfolded Protein Substrate: En Route to Chaperone Binding

Many proteins comprising of complex topologies require molecular chaperones to achieve their unique three-dimensional folded structure. The E.coli chaperone, GroEL binds with a large number of unfolded and partially folded proteins, to facilitate proper folding and prevent misfolding and aggregation...

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Detalles Bibliográficos
Autores principales: Nagpal, Suhani, Tiwari, Satyam, Mapa, Koyeli, Thukral, Lipi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4578939/
https://www.ncbi.nlm.nih.gov/pubmed/26394388
http://dx.doi.org/10.1371/journal.pcbi.1004496