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Decoding Structural Properties of a Partially Unfolded Protein Substrate: En Route to Chaperone Binding
Many proteins comprising of complex topologies require molecular chaperones to achieve their unique three-dimensional folded structure. The E.coli chaperone, GroEL binds with a large number of unfolded and partially folded proteins, to facilitate proper folding and prevent misfolding and aggregation...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2015
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4578939/ https://www.ncbi.nlm.nih.gov/pubmed/26394388 http://dx.doi.org/10.1371/journal.pcbi.1004496 |