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Systematic Prediction of Scaffold Proteins Reveals New Design Principles in Scaffold-Mediated Signal Transduction

Scaffold proteins play a crucial role in facilitating signal transduction in eukaryotes by bringing together multiple signaling components. In this study, we performed a systematic analysis of scaffold proteins in signal transduction by integrating protein-protein interaction and kinase-substrate re...

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Detalles Bibliográficos
Autores principales: Hu, Jianfei, Neiswinger, Johnathan, Zhang, Jin, Zhu, Heng, Qian, Jiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4578958/
https://www.ncbi.nlm.nih.gov/pubmed/26393507
http://dx.doi.org/10.1371/journal.pcbi.1004508