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Recombinant BCG Expressing Mycobacterium ulcerans Ag85A Imparts Enhanced Protection against Experimental Buruli ulcer

Buruli ulcer, an emerging tropical disease caused by Mycobacterium ulcerans (MU), is characterized by disfiguring skin necrosis and high morbidity. Relatively little is understood about the mode of transmission, pathogenesis, or host immune responses to MU infection. Due to significant reduction in...

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Detalles Bibliográficos
Autores principales: Hart, Bryan E., Hale, Laura P., Lee, Sunhee
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4579011/
https://www.ncbi.nlm.nih.gov/pubmed/26393347
http://dx.doi.org/10.1371/journal.pntd.0004046