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Molecular genetic mechanisms of allelic specific regulation of murine Comt expression

A functional allele of the mouse catechol-O-methyltransferase (Comt) gene is defined by the insertion of a B2 short interspersed repeat element in its 3′-untranslated region (UTR). This allele has been associated with a number of phenotypes, such as pain and anxiety. In comparison with mice carrying...

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Detalles Bibliográficos
Autores principales: Segall, Samantha K., Shabalina, Svetlana A., Meloto, Carolina B., Wen, Xia, Cunningham, Danielle, Tarantino, Lisa M., Wiltshire, Tim, Gauthier, Josée, Tohyama, Sarasa, Martin, Loren J., Mogil, Jeffrey S., Diatchenko, Luda
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wolters Kluwer 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4579042/
https://www.ncbi.nlm.nih.gov/pubmed/26067582
http://dx.doi.org/10.1097/j.pain.0000000000000258