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Molecular genetic mechanisms of allelic specific regulation of murine Comt expression
A functional allele of the mouse catechol-O-methyltransferase (Comt) gene is defined by the insertion of a B2 short interspersed repeat element in its 3′-untranslated region (UTR). This allele has been associated with a number of phenotypes, such as pain and anxiety. In comparison with mice carrying...
Autores principales: | Segall, Samantha K., Shabalina, Svetlana A., Meloto, Carolina B., Wen, Xia, Cunningham, Danielle, Tarantino, Lisa M., Wiltshire, Tim, Gauthier, Josée, Tohyama, Sarasa, Martin, Loren J., Mogil, Jeffrey S., Diatchenko, Luda |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Wolters Kluwer
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4579042/ https://www.ncbi.nlm.nih.gov/pubmed/26067582 http://dx.doi.org/10.1097/j.pain.0000000000000258 |
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