Severe Nephrotoxic Nephritis following Conditional and Kidney-Specific Knockdown of Stanniocalcin-1

BACKGROUND: Inflammation is the hallmark of nephrotoxic nephritis. Stanniocalcin-1 (STC1), a pro-survival factor, inhibits macrophages, stabilizes endothelial barrier function, and diminishes trans-endothelial migration of leukocytes; consistently, transgenic (Tg) overexpression of STC1 protects fro...

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Detalles Bibliográficos
Autores principales: Huang, Luping, Lou, Yahuan, Ju, Huiming, Zhang, Lin, Pan, Jenny Szu-Chin, Ross, April, Sun, Yuxiang, Truong, Luan D., Sheikh-Hamad, David
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4579070/
https://www.ncbi.nlm.nih.gov/pubmed/26393521
http://dx.doi.org/10.1371/journal.pone.0138440

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4579070/
https://www.ncbi.nlm.nih.gov/pubmed/26393521
http://dx.doi.org/10.1371/journal.pone.0138440

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