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Severe Nephrotoxic Nephritis following Conditional and Kidney-Specific Knockdown of Stanniocalcin-1
BACKGROUND: Inflammation is the hallmark of nephrotoxic nephritis. Stanniocalcin-1 (STC1), a pro-survival factor, inhibits macrophages, stabilizes endothelial barrier function, and diminishes trans-endothelial migration of leukocytes; consistently, transgenic (Tg) overexpression of STC1 protects fro...
Autores principales: | Huang, Luping, Lou, Yahuan, Ju, Huiming, Zhang, Lin, Pan, Jenny Szu-Chin, Ross, April, Sun, Yuxiang, Truong, Luan D., Sheikh-Hamad, David |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4579070/ https://www.ncbi.nlm.nih.gov/pubmed/26393521 http://dx.doi.org/10.1371/journal.pone.0138440 |
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