Light Chain Amyloid Fibrils Cause Metabolic Dysfunction in Human Cardiomyocytes

Light chain (AL) amyloidosis is the most common form of systemic amyloid disease, and cardiomyopathy is a dire consequence, resulting in an extremely poor prognosis. AL is characterized by the production of monoclonal free light chains that deposit as amyloid fibrils principally in the heart, liver,...

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Detalles Bibliográficos
Autores principales: McWilliams-Koeppen, Helen P., Foster, James S., Hackenbrack, Nicole, Ramirez-Alvarado, Marina, Donohoe, Dallas, Williams, Angela, Macy, Sallie, Wooliver, Craig, Wortham, Dale, Morrell-Falvey, Jennifer, Foster, Carmen M., Kennel, Stephen J., Wall, Jonathan S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4579077/
https://www.ncbi.nlm.nih.gov/pubmed/26393799
http://dx.doi.org/10.1371/journal.pone.0137716

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4579077/
https://www.ncbi.nlm.nih.gov/pubmed/26393799
http://dx.doi.org/10.1371/journal.pone.0137716

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