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Gpr116 Receptor Regulates Distinctive Functions in Pneumocytes and Vascular Endothelium

Despite its known expression in both the vascular endothelium and the lung epithelium, until recently the physiological role of the adhesion receptor Gpr116/ADGRF5 has remained elusive. We generated a new mouse model of constitutive Gpr116 inactivation, with a large genetic deletion encompassing exo...

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Detalles Bibliográficos
Autores principales: Niaudet, Colin, Hofmann, Jennifer J., Mäe, Maarja A., Jung, Bongnam, Gaengel, Konstantin, Vanlandewijck, Michael, Ekvärn, Elisabet, Salvado, M. Dolores, Mehlem, Annika, Al Sayegh, Sahar, He, Liqun, Lebouvier, Thibaud, Castro-Freire, Marco, Katayama, Kan, Hultenby, Kjell, Moessinger, Christine, Tannenberg, Philip, Cunha, Sara, Pietras, Kristian, Laviña, Bàrbara, Hong, JongWook, Berg, Tove, Betsholtz, Christer
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4579087/
https://www.ncbi.nlm.nih.gov/pubmed/26394398
http://dx.doi.org/10.1371/journal.pone.0137949