Cargando…

Diabetic Nephropathy Induced by Increased Ace Gene Dosage Is Associated with High Renal Levels of Angiotensin (1–7) and Bradykinin

Population studies have shown an association between diabetic nephropathy (DN) and insertion/deletion (I/D) polymorphism of the angiotensin-converting enzyme (ACE) gene (ACE in humans, Ace in mice). The aim was to evaluate the modulation of Ace copies number and diabetes mellitus (DM) on renal RAS a...

Descripción completa

Detalles Bibliográficos
Autores principales:	Bertoncello, Nádia, Moreira, Roseli Peres, Arita, Danielle Yuri, Aragão, Danielle S., Watanabe, Ingrid Kazue Mizuno, Dantas, Patricia S., Santos, Ralmony, Mattar-Rosa, Rodolfo, Yokota, Rodrigo, Cunha, Tatiana Sousa, Casarini, Dulce Elena
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Hindawi Publishing Corporation 2015
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4579315/ https://www.ncbi.nlm.nih.gov/pubmed/26442284 http://dx.doi.org/10.1155/2015/674047

Ejemplares similares

Both aldosterone and spironolactone can modulate the intracellular ACE/ANG II/AT1 and ACE2/ANG (1‐7)/MAS receptor axes in human mesangial cells
por: Stoll, Danielle, et al.
Publicado: (2019)

Purification and characterization of angiotensin converting enzyme 2 (ACE2) from murine model of mesangial cell in culture
por: Aragão, Danielle S., et al.
Publicado: (2011)

Catecholamines production by kidney tissue and mesangial cell culture is differentially modulated by diabetes
por: Moreira, Roseli Peres, et al.
Publicado: (2021)

Role of ACE2 in pregnancy and potential implications for COVID-19 susceptibility
por: Azinheira Nobrega Cruz, Nayara, et al.
Publicado: (2021)

Temporal changes in cardiac oxidative stress, inflammation and remodeling induced by exercise in hypertension: Role for local angiotensin II reduction
por: Silva, Sebastião D., et al.
Publicado: (2017)

Upregulation of ERK1/2-eNOS via AT2 Receptors Decreases the Contractile Response to Angiotensin II in Resistance Mesenteric Arteries from Obese Rats
por: Hagihara, Graziela N., et al.
Publicado: (2014)

Intra-Renal Angiotensin Levels Are Increased in High-Fructose Fed Rats in the Extracorporeal Renal Perfusion Model
por: Yokota, Rodrigo, et al.
Publicado: (2018)

Tonin Overexpression in Mice Diminishes Sympathetic Autonomic Modulation and Alters Angiotensin Type 1 Receptor Response
por: Jara, Zaira Palomino, et al.
Publicado: (2019)

Exercise-Induced Modulation of Angiotensin II Responses in Femoral Veins From 2-Kidney-1-Clip Hypertensive Rats
por: Chies, Agnaldo Bruno, et al.
Publicado: (2021)

ACE2 internalization induced by a SARS-CoV-2 recombinant protein is modulated by angiotensin II type 1 and bradykinin 2 receptors
por: Portales, Andrea Estefanía, et al.
Publicado: (2022)

Increase in Vascular Injury of Sodium Overloaded Mice May be Related to Vascular Angiotensin Modulation
por: Lima, Cintia Taniguti, et al.
Publicado: (2015)

ACE gene dosage determines additional autonomic dysfunction and increases renal angiotensin II levels in diabetic mice
por: de Moraes, Oscar Albuquerque, et al.
Publicado: (2018)

Plasma bradykinin and early diabetic nephropathy lesions in type 1 diabetes mellitus
por: Wheelock, Kevin M., et al.
Publicado: (2017)

Over diagnosis of bradykinin angioedema in patients treated with angiotensin-converting enzyme inhibitors or angiotensin II receptor blockers()
por: Douillard, Marie, et al.
Publicado: (2023)

N-Domain Isoform of Angiotensin I Converting Enzyme as a Marker of Hypertension: Populational Study
por: Maluf-Meiken, Leila C. V., et al.
Publicado: (2012)

Involvement of bradykinin and bradykinin B1 receptor in patients with endometriosis
por: Meng, Xin, et al.
Publicado: (2021)

The effect of insulin and enalapril on the potentiation of bradykinin-induced vasodilation by angiotensin-(1–7) in diabetes mellitus
por: Oliveira, MA, et al.
Publicado: (2003)

THU596 Heteromerization Of The Angiotensin II Type 1 Receptor And The Bradykinin Type 2 Receptor
por: Johnstone, Elizabeth K M, et al.
Publicado: (2023)

ACE polymorphism and diabetic nephropathy
por: Wiwanitkit, V.
Publicado: (2010)

Correction: Angiotensin-Converting Enzyme (ACE) 2 Overexpression Ameliorates Glomerular Injury in a Rat Model of Diabetic Nephropathy: A Comparison with ACE Inhibition
por: Liu, Chun Xi, et al.
Publicado: (2022)

Bradykinin receptor expression and bradykinin-mediated sensitization of human sensory neurons
por: Yi, Jiwon, et al.
Publicado: (2023)

Expression of ACE2, Soluble ACE2, Angiotensin I, Angiotensin II and Angiotensin-(1-7) Is Modulated in COVID-19 Patients
por: Osman, Ikram Omar, et al.
Publicado: (2021)

Neprilysin Inhibitors and Bradykinin
por: Campbell, Duncan J.
Publicado: (2018)

Cardiovascular Risk Associated with Interactions among Polymorphisms in Genes from the Renin-Angiotensin, Bradykinin, and Fibrinolytic Systems
por: Bentley, John P., et al.
Publicado: (2010)

Vasomotor Effects of Acetylcholine, Bradykinin, Noradrenaline, 5-Hydroxytryptamine, Histamine and Angiotensin II on the Mouse Basilar Artery
por: ISLAM, Md. Zahorul, et al.
Publicado: (2014)

Novel Pharmacology Following Heteromerization of the Angiotensin II Type 2 Receptor and the Bradykinin Type 2 Receptor
por: Johnstone, Elizabeth K. M., et al.
Publicado: (2022)

Potentiation of bradykinin actions by analogues of the bradykinin potentiating nonapeptide BPP(9α)
por: Mueller, Sylvia, et al.
Publicado: (2005)

Saccharomyces boulardii modulates oxidative stress and renin angiotensin system attenuating diabetes-induced liver injury in mice
por: Barssotti, Leticia, et al.
Publicado: (2021)

Efficacy and safety of two dosages of canrenone as add‐on therapy in hypertensive patients taking ace‐inhibitors or angiotensin II receptor blockers and hydrochlorothiazide at maximum dosage in a randomized clinical trial: The ESCAPE‐IT trial
por: Derosa, Giuseppe, et al.
Publicado: (2016)

Effect of Time of Day on Performance, Hormonal and Metabolic Response during a 1000-M Cycling Time Trial
por: Fernandes, Alan Lins, et al.
Publicado: (2014)

A Review of the Role of Bradykinin and Nitric Oxide in the Cardioprotective Action of Angiotensin-Converting Enzyme Inhibitors: Focus on Perindopril
por: Ancion, Arnaud, et al.
Publicado: (2019)

Combination of β Adrenergic Receptor Block and Renin–Angiotensin System Inhibition Diminished the Angiotensin II-Induced Vasoconstriction and Increased Bradykinin-Induced Vasodilation in Hypertension
por: Lezama-Martínez, Diego, et al.
Publicado: (2017)

Angiotensin Converting Enzyme (ACE) and ACE2 Bind Integrins and ACE2 Regulates Integrin Signalling
por: Clarke, Nicola E., et al.
Publicado: (2012)

Recombinant human ACE2: acing out angiotensin II in ARDS therapy
por: Zhang, Haibo, et al.
Publicado: (2017)

Bradykinin and the Pathogenesis of Hereditary Angioedema
por: Kaplan, Allen P
Publicado: (2011)

Cardiovascular Activities of of the bradykinin system
por: Sharma, Jagdish N.
Publicado: (2008)

Devil and angel in the renin–angiotensin system: ACE–angiotensin II–AT(1) receptor axis vs. ACE2–angiotensin-(1–7)–Mas receptor axis
por: Iwai, Masaru, et al.
Publicado: (2009)

Three key proteases – angiotensin-I-converting enzyme (ACE), ACE2 and renin – within and beyond the renin-angiotensin system
por: Guang, Cuie, et al.
Publicado: (2012)

DNA Damage and Augmented Oxidative Stress in Bone Marrow Mononuclear Cells from Angiotensin-Dependent Hypertensive Mice
por: Campagnaro, Bianca P., et al.
Publicado: (2013)

Administration of angiotensin II and a bradykinin B2 receptor blocker in midpregnancy impairs gestational outcome in guinea pigs
por: Valdés, Gloria, et al.
Publicado: (2014)

Cannot write session to /tmp/vufind_sessions/sess_fca897oaa3kcupb0i9sibfv6q4