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Genomic approaches for understanding the genetics of complex disease

There are thousands of known associations between genetic variants and complex human phenotypes, and the rate of novel discoveries is rapidly increasing. Translating those associations into knowledge of disease mechanisms remains a fundamental challenge because the associated variants are overwhelmi...

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Detalles Bibliográficos
Autores principales: Lowe, William L., Reddy, Timothy E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4579328/
https://www.ncbi.nlm.nih.gov/pubmed/26430153
http://dx.doi.org/10.1101/gr.190603.115