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Myxococcus CsgA, Drosophila Sniffer, and human HSD10 are cardiolipin phospholipases

Myxococcus xanthus development requires CsgA, a member of the short-chain alcohol dehydrogenase (SCAD) family of proteins. We show that CsgA and SocA, a protein that can replace CsgA function in vivo, oxidize the 2′-OH glycerol moiety on cardiolipin and phosphatidylglycerol to produce diacylglycerol...

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Detalles Bibliográficos
Autores principales: Boynton, Tye O'Hara, Shimkets, Lawrence Joseph
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4579348/
https://www.ncbi.nlm.nih.gov/pubmed/26338420
http://dx.doi.org/10.1101/gad.268482.115