A monoallelic-to-biallelic T-cell transcriptional switch regulates GATA3 abundance

Protein abundance must be precisely regulated throughout life, and nowhere is the stringency of this requirement more evident than during T-cell development: A twofold increase in the abundance of transcription factor GATA3 results in thymic lymphoma, while reduced GATA3 leads to diminished T-cell p...

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Detalles Bibliográficos
Autores principales: Ku, Chia-Jui, Lim, Kim-Chew, Kalantry, Sundeep, Maillard, Ivan, Engel, James Douglas, Hosoya, Tomonori
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2015
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4579350/
https://www.ncbi.nlm.nih.gov/pubmed/26385963
http://dx.doi.org/10.1101/gad.265025.115

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4579350/
https://www.ncbi.nlm.nih.gov/pubmed/26385963
http://dx.doi.org/10.1101/gad.265025.115

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