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REC-1 and HIM-5 distribute meiotic crossovers and function redundantly in meiotic double-strand break formation in Caenorhabditis elegans

The Caenorhabditis elegans gene rec-1 was the first genetic locus identified in metazoa to affect the distribution of meiotic crossovers along the chromosome. We report that rec-1 encodes a distant paralog of HIM-5, which was discovered by whole-genome sequencing and confirmed by multiple genome-edi...

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Detalles Bibliográficos
Autores principales: Chung, George, Rose, Ann M., Petalcorin, Mark I.R., Martin, Julie S., Kessler, Zebulin, Sanchez-Pulido, Luis, Ponting, Chris P., Yanowitz, Judith L., Boulton, Simon J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4579353/
https://www.ncbi.nlm.nih.gov/pubmed/26385965
http://dx.doi.org/10.1101/gad.266056.115