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Norepinephrine triggers metaplasticity of LTP by increasing translation of specific mRNAs

Norepinephrine (NE) is a key modulator of synaptic plasticity in the hippocampus, a brain structure crucially involved in memory formation. NE boosts synaptic plasticity mostly through initiation of signaling cascades downstream from beta (β)-adrenergic receptors (β-ARs). Previous studies demonstrat...

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Detalles Bibliográficos
Autores principales: Maity, Sabyasachi, Rah, Sean, Sonenberg, Nahum, Gkogkas, Christos G., Nguyen, Peter V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4579357/
https://www.ncbi.nlm.nih.gov/pubmed/26373828
http://dx.doi.org/10.1101/lm.039222.115