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Analysis of DLA-DQB1 and polymorphisms in CTLA4 in Cocker spaniels affected with immune-mediated haemolytic anaemia

BACKGROUND: Cocker spaniels are predisposed to immune-mediated haemolytic anaemia (IMHA), suggesting that genetic factors influence disease susceptibility. Dog leukocyte antigen (DLA) class II genes encode major histocompatibility complex (MHC) molecules that are involved in antigen presentation to...

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Detalles Bibliográficos
Autores principales: Threlfall, Anna J., Boag, Alisdair M., Soutter, Francesca, Glanemann, Barbara, Syme, Harriet M., Catchpole, Brian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4579385/
https://www.ncbi.nlm.nih.gov/pubmed/26401336
http://dx.doi.org/10.1186/s40575-015-0020-y