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Large-scale models of signal propagation in human cells derived from discovery phosphoproteomic data

Mass spectrometry is widely used to probe the proteome and its modifications in an untargeted manner, with unrivalled coverage. Applied to phosphoproteomics, it has tremendous potential to interrogate phospho-signalling and its therapeutic implications. However, this task is complicated by issues of...

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Detalles Bibliográficos
Autores principales: Terfve, Camille D. A., Wilkes, Edmund H., Casado, Pedro, Cutillas, Pedro R., Saez-Rodriguez, Julio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Pub. Group 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4579397/
https://www.ncbi.nlm.nih.gov/pubmed/26354681
http://dx.doi.org/10.1038/ncomms9033