Differentiated effects of the multimodal antidepressant vortioxetine on sleep architecture: Part 1, a pharmacokinetic/pharmacodynamic comparison with paroxetine in healthy men

We compared the effect of vortioxetine, paroxetine and placebo after three days of dosing on sleep architecture. This was a randomised, double-blind, four-way crossover, placebo-controlled, multiple-dose study in 24 healthy young men. Subjects received 20mg vortioxetine, 40mg vortioxetine, 20mg paro...

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Detalles Bibliográficos
Autores principales: Wilson, Sue, Højer, Astrid-Maria, Buchberg, Jeppe, Areberg, Johan, Nutt, David J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2015
Materias:
Original Papers
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4579403/
https://www.ncbi.nlm.nih.gov/pubmed/26253622
http://dx.doi.org/10.1177/0269881115599387

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4579403/
https://www.ncbi.nlm.nih.gov/pubmed/26253622
http://dx.doi.org/10.1177/0269881115599387

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