Whole-genome sequencing for prediction of Mycobacterium tuberculosis drug susceptibility and resistance: a retrospective cohort study

BACKGROUND: Diagnosing drug-resistance remains an obstacle to the elimination of tuberculosis. Phenotypic drug-susceptibility testing is slow and expensive, and commercial genotypic assays screen only common resistance-determining mutations. We used whole-genome sequencing to characterise common and...

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Detalles Bibliográficos
Autores principales: Walker, Timothy M, Kohl, Thomas A, Omar, Shaheed V, Hedge, Jessica, Del Ojo Elias, Carlos, Bradley, Phelim, Iqbal, Zamin, Feuerriegel, Silke, Niehaus, Katherine E, Wilson, Daniel J, Clifton, David A, Kapatai, Georgia, Ip, Camilla L C, Bowden, Rory, Drobniewski, Francis A, Allix-Béguec, Caroline, Gaudin, Cyril, Parkhill, Julian, Diel, Roland, Supply, Philip, Crook, Derrick W, Smith, E Grace, Walker, A Sarah, Ismail, Nazir, Niemann, Stefan, Peto, Tim E A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Science ;, The Lancet Pub. Group 2015
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4579482/
https://www.ncbi.nlm.nih.gov/pubmed/26116186
http://dx.doi.org/10.1016/S1473-3099(15)00062-6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4579482/
https://www.ncbi.nlm.nih.gov/pubmed/26116186
http://dx.doi.org/10.1016/S1473-3099(15)00062-6

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