Differential genomic imprinting regulates paracrine and autocrine roles of IGF2 in mouse adult neurogenesis

Genomic imprinting is implicated in the control of gene dosage in neurogenic niches. Here we address the importance of Igf2 imprinting for murine adult neurogenesis in the subventricular zone (SVZ) and in the subgranular zone (SGZ) of the hippocampus in vivo. In the SVZ, paracrine IGF2 is a cerebros...

Descripción completa

Detalles Bibliográficos
Autores principales: Ferrón, S. R., Radford, E. J., Domingo-Muelas, A., Kleine, I., Ramme, A., Gray, D., Sandovici, I., Constancia, M., Ward, A., Menheniott, T. R., Ferguson-Smith, A. C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Pub. Group 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4579569/
https://www.ncbi.nlm.nih.gov/pubmed/26369386
http://dx.doi.org/10.1038/ncomms9265

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4579569/
https://www.ncbi.nlm.nih.gov/pubmed/26369386
http://dx.doi.org/10.1038/ncomms9265

Ejemplares similares