Farnesoid X Receptor Inhibits Glucagon-Like Peptide-1 Production by Enteroendocrine L-cells

Bile acids (BA) are signalling molecules which activate the transmembrane receptor TGR5 and the nuclear receptor FXR. BA sequestrants (BAS) complex BA in the intestinal lumen and decrease intestinal FXR activity. The BAS-BA complex also induces Glucagon-Like Peptide-1 (GLP-1) production by L-cells w...

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Detalles Bibliográficos
Autores principales: TRABELSI, Mohamed-Sami, DAOUDI, Mehdi, PRAWITT, Janne, DUCASTEL, Sarah, TOUCHE, Véronique, SAYIN, Sama I., PERINO, Alessia, BRIGHTON, Cheryl A., SEBTI, Yasmine, KLUZA, Jérôme, BRIAND, Olivier, DEHONDT, Hélène, VALLEZ, Emmanuelle, DORCHIES, Emilie, BAUD, Grégory, SPINELLI, Valeria, HENNUYER, Nathalie, CARON, Sandrine, BANTUBUNGI, Kadiombo, CAIAZZO, Robert, REIMANN, Frank, MARCHETTI, Philippe, LEFEBVRE, Philippe, BÄCKHED, Fredrik, GRIBBLE, Fiona M., SCHOONJANS, Kristina, PATTOU, François, TAILLEUX, Anne, STAELS, Bart, LESTAVEL, Sophie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4579574/
https://www.ncbi.nlm.nih.gov/pubmed/26134028
http://dx.doi.org/10.1038/ncomms8629

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4579574/
https://www.ncbi.nlm.nih.gov/pubmed/26134028
http://dx.doi.org/10.1038/ncomms8629

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