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Linezolid, vancomycin and daptomycin modulate cytokine production, Toll-like receptors and phagocytosis in a human in vitro model of sepsis

Conventional antibiotics exhibit immunomodulatory properties beneficial in the treatment of sepsis. Antibiotic-resistant Gram-positive bacteria have become a problem in sepsis therapy, giving rise to increased use of last-resort antibiotics; for example, linezolid (LIN), vancomycin (VAN) and daptomy...

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Detalles Bibliográficos
Autores principales: Bode, Christian, Muenster, Stefan, Diedrich, Britta, Jahnert, Sebastian, Weisheit, Christina, Steinhagen, Folkert, Boehm, Olaf, Hoeft, Andreas, Meyer, Rainer, Baumgarten, Georg
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4579589/
https://www.ncbi.nlm.nih.gov/pubmed/25735844
http://dx.doi.org/10.1038/ja.2015.18