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Linezolid, vancomycin and daptomycin modulate cytokine production, Toll-like receptors and phagocytosis in a human in vitro model of sepsis
Conventional antibiotics exhibit immunomodulatory properties beneficial in the treatment of sepsis. Antibiotic-resistant Gram-positive bacteria have become a problem in sepsis therapy, giving rise to increased use of last-resort antibiotics; for example, linezolid (LIN), vancomycin (VAN) and daptomy...
Autores principales: | Bode, Christian, Muenster, Stefan, Diedrich, Britta, Jahnert, Sebastian, Weisheit, Christina, Steinhagen, Folkert, Boehm, Olaf, Hoeft, Andreas, Meyer, Rainer, Baumgarten, Georg |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4579589/ https://www.ncbi.nlm.nih.gov/pubmed/25735844 http://dx.doi.org/10.1038/ja.2015.18 |
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