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High-throughput transcriptomic analysis nominates proteasomal genes as age-specific biomarkers and therapeutic targets in prostate cancer

BACKGROUND: Although prostate cancer (PCa) is hypothesized to differ in nature between younger versus older patients, the underlying molecular distinctions are poorly understood. We hypothesized that high-throughput transcriptomic analysis would elucidate biological differences in PCas arising in yo...

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Detalles Bibliográficos
Autores principales: Zhao, S G, Jackson, W C, Kothari, V, Schipper, M J, Erho, N, Evans, J R, Speers, C, Hamstra, D A, Niknafs, Y S, Nguyen, P L, Schaeffer, E M, Ross, A E, Den, R B, Klein, E A, Jenkins, R B, Davicioni, E, Feng, F Y
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4579590/
https://www.ncbi.nlm.nih.gov/pubmed/25986914
http://dx.doi.org/10.1038/pcan.2015.22