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High-throughput transcriptomic analysis nominates proteasomal genes as age-specific biomarkers and therapeutic targets in prostate cancer
BACKGROUND: Although prostate cancer (PCa) is hypothesized to differ in nature between younger versus older patients, the underlying molecular distinctions are poorly understood. We hypothesized that high-throughput transcriptomic analysis would elucidate biological differences in PCas arising in yo...
Autores principales: | Zhao, S G, Jackson, W C, Kothari, V, Schipper, M J, Erho, N, Evans, J R, Speers, C, Hamstra, D A, Niknafs, Y S, Nguyen, P L, Schaeffer, E M, Ross, A E, Den, R B, Klein, E A, Jenkins, R B, Davicioni, E, Feng, F Y |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4579590/ https://www.ncbi.nlm.nih.gov/pubmed/25986914 http://dx.doi.org/10.1038/pcan.2015.22 |
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