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Differential expression of 2IgB7-H3 and 4IgB7-H3 in cancer cell lines and glioma tissues

B7-H3 protein is an important tumor antigen, but the expression of its isoforms, 4IgB7-H3 and 2IgB7-H3, in tumor tissues remains unknown due to the lack of specific monoclonal antibodies (mAbs). In the present study, a mAb (9C3) specifically recognizing 2IgB7-H3, but not 4IgB7-H3, was prepared. Usin...

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Detalles Bibliográficos
Autores principales: WANG, ZHENXIN, YANG, JIANFENG, ZHU, YANBO, ZHU, YUN, ZHANG, BIN, ZHOU, YINGHUI
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4579917/
https://www.ncbi.nlm.nih.gov/pubmed/26622819
http://dx.doi.org/10.3892/ol.2015.3611