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Intranasal Delivery of Apelin-13 Is Neuroprotective and Promotes Angiogenesis After Ischemic Stroke in Mice

Apelin is a peptide originally isolated from bovine stomach tissue extracts and identified as an endogenous ligand of the APJ receptor; recent work showed that apelin ameliorates the ischemic injury in the heart and the brain. Being an analogue to the angiotensin II receptor, the apelin/APJ signalin...

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Detalles Bibliográficos
Autores principales: Chen, Dongdong, Lee, Jinhwan, Gu, Xiaohuan, Wei, Ling, Yu, Shan Ping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4580122/
https://www.ncbi.nlm.nih.gov/pubmed/26391329
http://dx.doi.org/10.1177/1759091415605114