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Intranasal Delivery of Apelin-13 Is Neuroprotective and Promotes Angiogenesis After Ischemic Stroke in Mice
Apelin is a peptide originally isolated from bovine stomach tissue extracts and identified as an endogenous ligand of the APJ receptor; recent work showed that apelin ameliorates the ischemic injury in the heart and the brain. Being an analogue to the angiotensin II receptor, the apelin/APJ signalin...
Autores principales: | Chen, Dongdong, Lee, Jinhwan, Gu, Xiaohuan, Wei, Ling, Yu, Shan Ping |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
SAGE Publications
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4580122/ https://www.ncbi.nlm.nih.gov/pubmed/26391329 http://dx.doi.org/10.1177/1759091415605114 |
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